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- Enjoy breakfast all day long at Chris @ The Docket, a popular restaurant with everything from eggs to pizza and hamburgers served on their all-day menu. Visitors to St. Louis love to dine at Chris @ The Docket and as it is within walking distance from 21c Museum St Louis Hotel, it makes the perfect spot to grab breakfast or a late-night bite.
- Sip on a tasty cocktail at Thaxton Speakeasy. A Prohibition-era themed bar with a required password entry, the speakeasy is located in a historic building in a ritzy cellar making it spot visitors enjoy going to on a night out.
- Grab a bite at the local downtown Mediterranean spot known for gyros and tasty rice bowls. Only a few blocks down from 21c Museum Hotel St Louis, Medina Grill offers a delicious and healthy option for visitors to the area with restricted dietary needs or who just love Mediterranean food.