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Each of the 173 guestrooms at 21c Museum Hotel St. Louis was designed for both comfort and style. Guestrooms and suites at the boutique hotel feature high ceilings and large windows and are furnished with custom-designed furniture.

Deluxe King

The Deluxe King guestrooms come outfitted with a king-size bed, cozy seating area with a table and glass-enclosed shower.

Luxury Double Queen
The Luxury Double Queen guestrooms come outfitted with two queen-size beds, seating area with a table and bath tub, plus all 21c luxury amenities.

Loft Double Queen
The Loft Double Queen double-height guestrooms come outfitted with two queen-size beds, a seating area with table and bath tub.

Luxury King Suite
The Luxury King Suite is a light-filled one bedroom suite with a king-size bed, a separate living area with a table and office. The bathroom features a dual sink vanity, soaking tub, and glass-enclosed shower.

Library Suite
The Library King Suite is a one-of-a-kind, historic wood-paneled studio suite featuring a king-size bed and separate living and working areas with non-working original fireplace. The bathroom features a glass-enclosed shower.

21c Suite
The 21c King Suite is a two-story duplex suite with expansive windows, large living and dining area with fireplace and kitchenette and powder room downstairs. Upstairs features a personal fitness loft, spacious bedroom and en-suite dressing table and bathroom.

Amenities:
  • 50'' HDTV flat screen television
  • Alarm Clock/Docking Station
  • Lavazza Coffee
  • Malin+Goetz Bath Amenities
  • Original Artwork by Missouri-based artists
  • Pet-Friendly Rooms
  • Free WiFi
  • Luxurious Bedding
  • Laundry Service
  • In-Room Dining
  • 24-Hour Fitness Center
  • Historic Indoor Pool
  • Sauna
  • Steam Room