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370 Commonwealth Ave Boston, Massachusetts 02215
The original property opened in 1925. A member of Historic Hotels of America since 2024.
As witnesses to the Grand Parisian-inspired redevelopment and economic success of Boston’s Back Bay neighborhood, former Harvard University president Charles William Eliot and his family wanted a presence for the university in this neighborhood. The hotel, built next to the Harvard alumni club, initially housed visiting and retired professors. It would change hands several times after the Great Depression before ultimately becoming one of the city’s preferred entertainment, cuisine and holiday destinations in the latter half of the twentieth century.
Today’s guests can enjoy the historic charm of the hotel and its surroundings from one of 95 comfortable modernized deluxe rooms and suites. Guests are invited to indulge at UNI, the hotel’s celebrated resident Japanese izakaya, or gastropub. The restaurant, with its innovative sushi, small plates, and sake selection, is recognized as the best in Boston by Zagat and Boston Magazine and features a James Beard Award winning executive chef.
The Mission Inn Hotel & Spa has been named to these Historic Hotels of America Top 25 Lists
The 2025 Top 25 Historic Hotels of America Most Romantic Hotels

Location Map
Relax in the Parisian-inspired boulevards and parks of the Back Bay, a convenient gateway for a greater view of Boston.

Discover
Discover the hotel’s elegant entryway, decorated throughout the year with everything from wisteria to holiday lights.

Explore
Explore Boston’s Revolutionary War history through visits to the Old North Church and Boston National Historic Park.

Experience
Experience a stroll through the hotel's Back Bay neighborhood, encountering local architecture, parks and shopping.
