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Driving Directions
- I-75 N to West 5th St in Cincinnati.
- Take exit 1C from I-75 N
- Follow West 5th St to Vine St turn left
- Turn right on 7th St
- Turn right on Walnut St
- 21c Museum Hotel Cincinnati will be on the left #609
Nearest Airport
Cincinnati / Northern Kentucky International Airport (CVG): 13.1 miles/16-24 minutes away
Hotel Address
609 Walnut Street, Cincinnati
Ohio, United States 45202
Historic Hotels of America Recommended Points of Interest
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American Sign Museum
Explore historical American signage at the American Sign Museum.
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Cincinnati Art Museum
Experience some of the finest art in the country at the Cincinnati Art Museum.
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Cincinnati Museum Center at Union Terminal
Discover kid-friendly activities at the Cincinnati Museum Center at Union Terminal.
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Cincinnati Zoo & Botanical Garden
Explore the wide variety of animals at the Cincinnati Zoo & Botanical Garden.
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Harding Home Presidential Site
Discover the residence of former U.S. President Warren G. Harding.
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Krohn Conservatory
Spend time outside in Cincinnati at the famous Krohn Conservatory.
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Mt. Airy Forest
Hike through the verdant Mt. Airy Forest.
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National Underground Railroad Freedom Center
Experience the historical legacy of the Underground Railroad.
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Newport Aquarium
Discover the aquatic life on display at the Newport Aquarium.
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Rutherford B. Hayes Presidential Library & Museums
Experience the legacy of former U.S. President Rutherford B. Hayes.
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Southgate Street School
Visit this historic school, which played host to African American students in the community from 1866 until integration in the 1950s.
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William Howard Taft National Historic Site
Explore the home of former U.S. President William Howard Taft.